The Department of Twin Research is co-ordinating a 5 year EU Framework 7 Large Collaborative Project (HEALTH-F2-2008-00) which started in January 2008 with funding of €11,924,000 and 10 research partners from 6 European countries.
TREAT-OA’s objectives are:
- to define the role of genes to understand the molecular pathways involved in disease aetiology
- to identify genes and biochemical markers consistently associated with risk and progression of hip and knee OA
- to analyze the molecular pathways to identify targets for pharmacological intervention
- to develop in vivo models by the use of transgenic animal laboratory OA model systems and 5) to develop a panel of genetic and biochemical diagnostics for risk and progression of OA.
As of February 2011 TREAT-OA has generated over 40 peer reviewed publications. To find out more please go to http://www.treatoa.eu/.