2004

Altman RD, Bloch D.A, Dougados M, Hochberg M, Lohmander S, Pavelka K, Spector TD, Vignon E. Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group. Osteoarthritis and Cartilage 2004, 12: 515-524. 

Spector TD. Strontium Ranelate: the first drug in a new class for osteoporosis. Future Prescriber 2004, 5 (2): 13-16

Spector TD, Ralston SH. Genetic factors in osteoporosis. Medicographia 2004 3 (26): 221-226.

Cherkas LF, Oelsner E, Mak YT, Valdes A, Spector TD. Genetic influences on female infidelity and number of sexual partners in humans: A linkage and association study of the role of the vasopreswsin receptor gene (AVPR1A). Twin Research 2004, 7 (6): 649-58 

de Lange M, Spector TD, Andrew T. Genome-Wide Scan for Blood Pressure Suggests Linkage to Chromosome 11, andReplication of Loci on 16, 17, and 22. Hypertension 2004 Dec;44 (6):872-7 

Williams MK, Cherkas LF, Spector TD, MacGregor AJ. A common genetic factor underlies hypertension and other cardiovascular disorders. BMC Cardiovascular Disorders 2004 Nov 1;4 (1):20 

Spector TD. Osteoporosis – NICE sets new challenges for London. Capital Doctor Sept 2004, 36:22.

Greenfield JR, Samaras K, Jenkins AB, Kelly PJ, Spector TD, and Campbel LV. Do gene-environment interactions influence fasting plasma lipids? A study of twins.Eur J Clin Invest, Sep 1, 2004; 34(9): 590-8.

Hammond CJ, Andrew T, Tat Mak Y, Spector TD. A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins. Am J Hum Genet. Aug 2004; 75(2):294-304. 

Hakim AJ, Cherkas LF, Grahame R, Spector TD, MacGregor AJ. The genetic epidemiology of joint hypermobility: a population study of female twins. Arthritis Rheum. Aug 2004; 50(8):2640-4.

Valdes AM, Hart DJ, Jones KA, Surdulescu G, Swarbrick P, Doyle DV, Schafer AJ, Spector TD. Association study of candidate genes for the prevalence and progression of knee osteoarthritis. Arthritis Rheum. Aug 2004; 50(8):2497-507. 

Dong Y, Zhu H, Wang X, Dalageorgou C, Carter N, Spector TD, Snieder H. Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins. Pharmacogenetics Jul 2004; 14(7): 419-427. 

Meunier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, Spector TD, Cannata J, Balogh A, Lemmel EM, Pors-Nielsen S, Rizzoli R, Genant HK, Reginster JY. The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women With Postmenopausal Osteoporosis. Obstet Gynecol Surv. Jul 2004; 59(7):526-527. 

Garner C, Silver N, Best S, Menzel S, Martin C, Spector TD, Thein SL. A Quantitative Trait Locus on Chromosome 8q Influences the Switch From Fetal to Adult Hemoglobin. Blood 2004 Oct 1;104 (7):2184-6 

Smith AJ, Keen LJ, Billingham MJ, Perry MJ, Elson CJ, Kirwan JR, Sims JE,Doherty M, Spector TD, Bidwell JL. Extended haplotypes and linkage disequilibrium in the IL1R1-IL1A-IL1B-IL1RN gene cluster: association with knee osteoarthritis.Genes Immun. Jun 10, 2004. 

Greenfield JR, Samaras K, Jenkins AB, Kelly PJ, Spector TD, Gallimore JR, Pepys MB, Campbell LV. Obesity Is an Important Determinant of Baseline Serum C-Reactive Protein Concentration in Monozygotic Twins, Independent of Genetic Influences. Circulation. Jun 2004; 109(24):3022-8

Mak YT, Hampson G, Beresford JD, Spector TD. Variations in genome-wide gene expression in identical twins – a study of primary osteoblast-like culture from female twins discordant for osteoporosis.BMC Genet. Jun 4, 2004. 

Knapp KM, Blake GM, Spector TD, Fogelman I. Can the WHO definition of osteoporosis be applied to multi-site axial transmission quantitative ultrasound? Osteoporos Int. May 2004;15(5):367-74.

Spector TD, Selby PL. Strontium ranelate: a new treatment for osteoporosis. Osteoporosis review 2004, 12 (4): 08-10. 

Desai Anup V, Cherkas Lynn F, Spector Tim D, Williams Adrian J. Genetic Influences in Self-Reported Symptoms of Obstructive Sleep Apnoea and Restless Legs: A Twin Study. Twin Research 2004; 7(6):589-595.

MacGregor AJ, Andrew T, Sambrook PN, Spector TD. Structural, Psychological, and genetic influences on low back and neck pain: A study of adult female twins. Arthritis Rheum. Apr 15, 2004; 51(2):160-7. 

Spector TD, MacGregor AJ. Risk factors for osteoarthritis: Genetics. Osteoarthritis and Cartilage. 2004, 12 Suppl A: S39-44.

Dunn EJ, Ariens RA, De Lange M, Snieder H, Turney JH, Spector TD, Grant PJ. Genetics of fibrin clot structure: A twin study. Blood Mar 1, 2004; 103(5):1735-40 

Van Den Oord EJ, MacGregor AJ, Snieder H, Spector TD. Modeling with measured genotypes: effects of the vitamin d receptor gene, age,and latent genetic and environmental factors on bone mineral density. Behav Genet. Mar 2004; 34(2):197-206.

Wilson SG, Reed PW, Andrew T, Barber MJ, Lindersson M, Langdown M, Thompson D, Thompson E, Bailey M, Chiano M, Kleyn PW, Spector TD. A genome-screen of a large twin cohort reveals linkage for quantitative ultrasound of the calcaneus to 2q33-37 and 4q12-21. J Bone Miner Res. Feb 2004; 19(2):270-7

Meunier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, Spector TD, Cannata J, Balogh A, Lemmel EM, Pors-Nielsen S, Rizzoli R, Genant HK, Reginster JY. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med. Jan 29, 2004; 350(5):459-68.

MacGregor AJ, Gallimore JR, Spector TD, Pepys MB. Genetic Effects on Baseline Values of C-Reactive Protein and Serum Amyloid A Protein: A Comparison of Monozygotic and Dizygotic. Twins.Clin Chem. Jan 2004; 50(1):130-4