2007

Cherkas LF, Williams FMK, Carter L, Howell K, Black CM, Spector TD, MacGregor AJ. The heritability of raynaud’s phenomenon and vascular responsiveness to cold: a study of adult female twins. Arthritis Care & Research 2007; 57 (3):524-8

De Moor MH, Spector TD, Cherkas LF, Falchi M, Hottenga JJ, Boomsma DI & De Geus EJ. Genome-wide linkage scan for athlete status in 700 British female DZ twin pairs. Twin Res Hum Genet 2007 Dec;10(6):812-20.

Keskitalo K, Tuorila H, Spector TD, Cherkas LF, Knaapila A, Silventoinen K, Perola M. Same genetic components underlie different measures of sweet taste preference. Am J Clin Nutr. 2007 Dec;86(6):1663-9 

Richards JB, Valdes AM, Gardner JP, Paximadas D, Kimura M, Nessa A, Lu X, Surdulescu GL, Swaminathan R, Spector TD, Aviv A. Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women. Am J Clin Nutr 2007; 86: 1420-5 

Valdes AM, Loughlin J, VanOene M, Chapman K, Surdulescu GL, Doherty M, Spector TD. Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP and FRZB with genetic susceptibility to osteoarthritis of the knee. Arthritis & Rheumatism 2007; 56(1):137-146 

Gosden RG, Treloar SA, Martin NG, Cherkas LF, Spector TD, Faddy MJ, Silber SJ. Prevalence of premature ovarian failure in monozygotic and dizygotic twins. Human Reproduction 2007; Feb 22(2):610-5 

Richards JB, Cherkas LF, Spector TD. An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults. Current Medical Research Opinions 2007; 23(2):293-299 

Zhai G, Hart DJ, Kato BS, MacGregor A, Spector TD. Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study. Osteoarthritis & Cartilage 2007;15:222-225 

Zhang F, Zhai G, Kato BS, Hart DJ, Hunter D, Spector TD, Ahmadi K. Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population. Osteoarthritis & Cartilage 2007 June; 15 (6):624-9 

Steer SE, Williams FMK, Kato B, Gardner JP, Norman PJ, Hall MA, Kimura M, Vaughan R, Aviv A, Spector TD. Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration. Ann Rheum Dis. 2007 Apr; 66 (4):476-480 

Ioannidis JP, Ng MY, Sham PC, Zintzaras E, Lewis C, Deng H, Econs MJ, Karasik D, Devoto M, Kammerer C, Spector TD, Andrew T, Cupples A, Foroud T, Keil D, Koller DL, Langdahl BL, Mitchell B, Peacock M, Recker R, Hui S, Katia S, Spotila L, Uitterlinden AG, Wilson S, Kung AW, Ralston SH. Meta-analysis of genome wide scans provides evidence for gender and site specific regulation of bone mass. JBMR 2007;22 (2):173-183 

Jamshidi Y, Gooljar SB, Snieder H, Wang X, Ge D, Swaminathan R, Spector TD. O’dell SD. SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. Atherosclerosis 2007 Oct;194 (2):e26-33

Valdes AM, Richards JB, Gardner JP, Swaminathan R, Kimura M, Lu X, Aviv A, Spector TD. Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis. Osteoporosis Int 2007 Sep; 18 (9):1203-10 

Richards JB, Valdes AM, Burling K, Perks UC,Spector TD. Serum adiponectin and bone mineral density in women . Journal of Clinical Endocrinology & Metabolism 2007; 92(4):1517-1523 

Jamshidi Y, Snieder H, Ge D, Spector TD, O’Dell SD. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) 2007 Jan; 15(1):5-9 

Zhai G, Ding C, Cicuttine F, Jones G. A longitudinal study of the association between knee alignment and change in cartilage volume and chondral defects in a largely non-osteoarthritic population. Journal of Rheumatology 2007 Jan; 34 (1):181-6 

Livshits G, Kato BS, Zhai G, Hart DJ, Hunter D, MacGregor AJ, Williams FMK, Spector TD. Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of quantitative trait loci on chromosome 2 and 19. Ann Rheum Dis 2007; 66 (5):623-7 

Knaapila A, Tuorila H, Silventoinen K, Keskitalo K, Kallela M, Wessman M, peltonen L, Cherkas LF, Spector TD, Perola M. Food neophobia shows heritable variation in humans. Physiol Behav 2007 Aug 15;91(5):573-8

Williams FM, Manek NJ, Sambrook PN, Spector TD, MacGregor AJ. Schmorl’s nodes: Common, highly heritable, and related to lumbar disc disease. Arthritis Care & Research 2007; 57 (5):855-860 

Healey PR, Mitchell P, Gilbert CE, Lee AJ, Ge D, Snieder H, Spector TD, Hammond CJ. The inheritance of peripapillary atrophy. Invest Ophthalmol Vis Sci. 2007 Jun; 48 (6):2529-34 

Mullin BH, Spector TD, Curtis CC, Ong GN, Hart DJ, Hakim AJ, Worthy T, Wilson SG. Polymorphisms in ALOX12, but not ALOX15, are significantly associated with BMD in postmenopausal women. Calcif Tissue Int. 2007 Jul; 81 (1): 10-7 

Majava M, Bishop PN, Hagg P, Scott PG, Rice A, Inglehearn C, Hammond CJ, Spector TD, Ala-Kokko L, Mannikko M. Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia. Hum Mutat 2007; 28 (4):336-44

Menzel S, Garner C, Gut I, Matsuda F, Yamaguchi M, Heath S, Foglio M, Zelenika D, Boland A, Rooks H, Best S, Spector TD, Farrall M, Lathrop M, Thein SL. A QTL influencing F cell production maps to a gene encoding a Zinc-finger protein on chromososme 2p15. Nature Genetics 2007 Oct;39(10):1197-9 

Bataille V, Kato BS, Falchi M, Gardner J, Kimura M, Lens M, Perks U, Valdes AM, Bennett DC, Aviv A, Spector TD. Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo. Cancer Epidemiol Biomarkers Prev 2007;16(7):1499-502 

Thein SL, Menzel S, Peng X, Best S, Jiang J, Close J, Silver N, Gerovasilli A,Ping C, Yamaguchi M, Wahlberg K, Ulug P, Spector TD, Garner C, Matsuda F, Farrall M, Lathrop M. Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11346-51 

Jamshidi Y, Kyriakou T, Gooljar SB, Collins LJ, Lane CA, Snieder H, Wang X, Spector TD, O’dell SD. Common STAT3 Variants Are Not Associated With Obesity or Insulin Resistance in Female Twins. Obesity (Silver Spring). 2007 Jul;15(7):1634-1639 

Prainsack B, Cherkas LF, Spector TD. Attitudes towards human reproductive cloning, assisted reproduction and gene selection: a survey of 4600 British twins. Hum Reprod. 2007 Aug;22 (8):2302-8 

Bruyere O, Roux C, Detilleux J, Slosman DO, Spector TD, Fardellone P, Brixen K, Devogelaer JP, Diaz-Curiel M, Albanese C, Kaufman JM, Pors-Nielsen S, Reginster JY. Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. J Clin Endocrinol Metab. 2007 Aug; 92(8):3076-81 

Perola M, Sammalisto S, Hiekkalinna T, Martin NG, Visscher PM, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga JJ, Christensen K, Kyvik KO, Sorensen TI, Pedersen NL, Magnusson PK, Spector TD, Widen E, Silventoinen K, Kaprio J, Palotie A, Peltonen L; GenomEUtwin Project. Combined Genome Scans for Body Stature in 6,602 European Twins: Evidence for Common Caucasian Loci. PLoS Genet. 2007 Jun 8;3(6):e97 

Livshits G, Kato BS, Wilson SG, Spector TD. Linkage of genes to total lean body mass in normal women. J Clin Endocrinol Metab. 2007 Aug; 92(8):3171-6 

Zhang F, Kato BS, Gardner JP, Kimura M, Spector TD, Ahmadi KR. Lack of association between leukocyte telomere length and genetic variants in two ageing-related candidate genes. Mech Ageing Dev. 2007 Jul-Aug; 128 (7-8):415-22 

Zhai G, Valdes AM, Cherkas L, Clement G, Strachan D, Spector TD.The Interaction of Genes and Smoking on Forced Expiratory Volume: A Classic Twin Study. Chest 2007 Dec; 132 (6):1772-7 

Teucher B, Skinner J, Skidmore PM, Cassidy A, Fairweather-Tait SJ, Hooper L, Roe MA, Foxall R, Oyston SL, Cherkas LF, Perks UC, Spector TD, MacGregor AJ. Dietary patterns and heritability of food choice in a UK female twin cohort. Twin Res Hum Genet. 2007 Oct; 10 (5):734-48 

Siva A, De Lange M, Clayton D, Monteith S, Spector TD, Brown MJ. The heritability of plasma homocysteine, and the influence of genetic variation in the homocysteine methylation pathway. QJ Med. 2007 Aug;100 (8):495-9

Chinappen-Horsley U, Blake GM, Fogelman I, Spector TD. A Method for Determining Skeletal Lengths from DXA Images. BMC Musculoskelet Disord. 2007 Nov 16;8(1):113

Barwell J, Pangon L, Georgiou A, Docherty Z, Kesterton I, Ball J, Camplejohn R, Berg J, Aviv A, Gardner J, Kato BS, Carter N, Paximadas D, Spector TD, Hodgson S. Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity? Br J Cancer. 2007 Dec 17; 97 (12):1696-700 

Richards JB, Valdes AM, Gardner JP, Paximadas D, Kimura M, Nessa A, Lu X, Surdulescu GL, Swaminathan R, Spector TD, Aviv A. Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women. Am J Clin Nutr. 2007 Nov;86(5):1420-1425. 

Krzeski P, Buckland-Wright C, Balint G, Cline GA, Stoner K, Lyon R, Beary J, Aronstein WS, Spector TD. Development of musculoskeletal toxicity without clear benefit after administration of PG 116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12 month, double-blind, placebo-controlled study. Arthritis Res Ther. 2007 Oct 24;9(5):R109 

Williams FM, Spector TD. The genetics of osteoporosis. Acta Reumatol Port. 2007 Jul-Sep;32(3):231-40.

Carter AM, Cymbalista CM, Spector TD, Grant PJ; EuroCLOT Investigators. Heritability of clot formation, morphology, and lysis: the EuroCLOT study. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2783-9. 

Norbury TA, MacGregor AJ, Urwin J, Spector TD, McMahon SB. Heritability of responses to painful stimuli in women: a classical twin study. Brain. 2007 Nov;130(Pt 11):3041-9.

Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P 3rd, Tyndale RF, Swan GE, Benowitz NL. Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenet Genomics. 2007 Dec;17(12):1007-15

Arkadianos I, Valdes AM, Marinos E, Florou A, Gill RD, Grimaldi KA. .Improved weight management using genetic information to personalize a calorie controlled diet. Nutr J. 2007 Oct 18;6:29

Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J, Erlich HA, Cucca F, Pugliese A, Steenkiste A, Dorman JS, Caillat-Zucman S, Hermann R, Ilonen J, Lambert AP, Bingley PJ, Gillespie KM, Lernmark A, Sanjeevi CB, Rønningen KS, Undlien DE, Thorsby E, Petrone A, Buzzetti R, Koeleman BP, Roep BO, Saruhan-Direskeneli G, Uyar FA, Günoz H, Gorodezky C, Alaez C, Boehm BO, Mlynarski W, Ikegami H, Berrino M, Fasano ME, Dametto E, Israel S, Brautbar C, Santiago-Cortes A, Frazer de Llado T, She JX, Bugawan TL, Rotter JI, Raffel L, Zeidler A, Leyva-Cobian F, Hawkins BR, Chan SH, Castano L, Pociot F, Nerup J. Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens. 2007 Aug;70(2):110-27 

Swan GE, Jack LM, Valdes AM, Ring HZ, Ton CC, Curry SJ, McAfee T. Joint effect of dopaminergic genes on likelihood of smoking following treatment with bupropion SR. Health Psychol. 2007 May;26(3):361-8

Steenkiste A, Valdes AM, Feolo M, Hoffman D, Concannon P, Noble J, Schoch G, Hansen J, Helmberg W, Dorman JS, Thomson G, Pugliese A; 13th IHWS 1 Diabetes Component participating investigators. 14th International HLA and Immunogenetics Workshop: report on the HLA component of type 1 diabetes. Tissue Antigens. 2007 Apr;69 Suppl 1:214-25.