Scientific Publications

  • 2017

    Arredouani A, Stocchero M, Culeddu N, Moustafa JE; D.E.S.I.R. Study Group, Tichet J, Balkau B, Brousseau T, Manca M, Falchi M.Erratum. Metabolomic Profile of Low-Copy Number Carriers at the Salivary α-Amylase Gene Suggests a Metabolic Shift Toward Lipid-Based Energy Production. Diabetes. 2017 Apr;66(4):1097. Epub 2017 Feb 13. PMCID:PMC5360297.  van den Berg ME, Warren HR, Cabrera CP, […]

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  • 2016

    Al Muftah WA, Al-Shafai M, Zaghlool SB, Visconti A, Tsai PC, Kumar P, Spector T, Bell J, Falchi M, Suhre K. Epigenetic associations of type 2 diabetes and BMI in an Arab population. Clin Epigenetics. 2016 Jan 28;8:13. eCollection. PMCID: PMC4730771. Allegri M, De Gregori M, Minella CE, Klersy C, Wang W, Sim M, Gieger […]

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  • 2015

    Agricola R, Leyland KM, Bierma-Zeinstra SM, Thomas GE, Emans PJ, Spector TD, Weinans H, Waarsing JH, Arden NK. Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford). Rheumatology (Oxford). 2015 Nov;54(11):2033-41. Epub 2015 Jul 1. PMID: 26139655.  Allum F, Shao […]

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  • 2014

    Albrecht E, Sillanpää E, Karrasch S, Alves AC, Codd V, Hovatta I, Buxton JL, Nelson CP, Broer L, Hägg S, Mangino M, Willemsen G, Surakka I, Ferreira MA, Amin N, Oostra BA, Bäckmand HM, Peltonen M, Sarna S, Rantanen T, Sipilä S, Korhonen T, Madden PA, Gieger C, Jörres RA, Heinrich J, Behr J, Huber […]

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  • 2013

    Amin V, Behrman JR, Spector TD. Does More Schooling Improve Health Outcomes and Health Related Behaviors? Evidence from U.K. Twins. Econ Educ Rev. 2013 Aug 1;35. PMCID: PMC3885175. Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L,Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose […]

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  • 2012

    Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM; kConFab Investigators, Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G, Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L, Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson […]

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  • 2011

    Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM; kConFab Investigators, Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G, Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L, Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson DF, Kiemeney LA, Thorsteinsdottir U, Stefansson K, van Rooij FJ, Aulchenko YS, Hottenga JJ, Rivadeneira FR, Hofman A, Uitterlinden AG, Hammond CJ, Shin SY, Ikram A, Witteman JC, Janssens AC, Snieder H, Tiemeier H, Wolfenbuttel BH, Oostra BA, Heath AC, Wichmann E, Spector TD, Grabe HJ, Boomsma DI, Martin NG, van Duijn CM. Genome-wide association analysis of coffee drinking suggests association with

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  • 2010

    Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJL, Beckmann J, Bilo HJG, Bochud M, Brown MJ, Caulfield MJ, Connell JMC, Cook HT, Cotlarciuc I, Smith GD, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, van der Heide JJH, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Toby Johnson33, de Jong PE, Kleefstra N, Lagou V, Lapsley M,

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  • 2009

    Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC,

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  • 2008

    Anderson CA, Zhu G, Falchi M, van den Berg SM, Treloar SA, Spector TD, Martin NG, Boomsma DI, Visscher PM, Montgomery GW. A genome-wide linkage scan for age-at-menarche in three populations of European descent. J Clin Endocrinol Metab. 2008 October; 93 (10):3965-3970

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  • 2007

    Krzeski P, Buckland-Wright C, Balint G, Cline GA, Stoner K, Lyon R, Beary J, Aronstein WS, Spector TD. Development of musculoskeletal toxicity without clear benefit after administration of PG 116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12 month, double-blind,

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  • 2006

    Smith AJ, Gidley J, Sandy JR, Perry MJ, Elson CJ, Kirwan JR, Spector TD, Doherty M, Bidwell JL, Mansell JP. Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis? Osteoarthritis Cartilage 2005 Jul; 13 (7): 608-13.

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  • 2005

    Maheu E, Cadet C, Marty M, Dougados M, Ghabri S, Kerloch I, Mazieres B, Spector TD, Vignon E, Lequesne MG. Reproducibility and sensibility to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval. Arthritis Research & Therapy 2005; 7 (6): R1375-85.

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  • 2004

    Altman RD, Bloch D.A, Dougados M, Hochberg M, Lohmander S, Pavelka K, Spector TD, Vignon E. Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group. Osteoarthritis and Cartilage 2004, 12: 515-524.

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  • 2003

    Ariens RA, de Lange M, Snieder H, Boothby M, Spector TD, Grant PJ. Activation markers of coagulation and fibrinolysis in twins: Heritability of the prethrombotic state. Lancet 2002 Feb 23;359(9307):667-71

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  • 2002

    Arden NK, Major P, Poole JR, Keen RW, Vaja S, Swaminathan R, Cooper C, Spector TD. Size at birth, adult intestinal calcium absorption and 1,25(OH)(2) vitamin D. QJM 2002 Jan;95(1):15-21 

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  • 2001

    Ahmadi KR, Hall MA, Norman P, Vaughan RW, Snieder H, Spector TD, Lanchbury JS. Genetic determinism in the relationship between human CD4 (+) and CD8 (+) T lymphocyte populations? Genes Immun 2001;2(7):381-7.

    Andrew T, Hart DJ, Snieder H, de Lange M, Spector TD, MacGregor AJ. Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women.

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  • 2000

    Bataille V, Snieder H, MacGregor AJ, Sasieni P, Spector TD. Genetics of risk factors for melanoma: an adult twin study of nevi and freckles. J Natl Cancer Inst 2000;92(6):457-63. 

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  • 1999

    Etherington J, Keeling J, Bramley R, Swaminathan R, McCurdie I, Spector TD. The effects of 10 weeks military training on heel ultrasound and bone turnover. Calcif Tissue Int 1999;64(5):389-93. 

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  • 1998

    Boomsma DI, Snieder H, de Geus EJ, van Doornen LJ. Heritability of blood pressure increases during mental stress. Twin Res 1998;1(1):15-24.

    Cicuttini FM, Baker J, Hart DJ, Spector TD. Relation between Heberden’s nodes and distal interphalangeal joint osteophytes and their role as markers of generalised disease. Ann Rheum Dis 1998;57(4):246-8.

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  • 1997

    MacGregor AJ, Griffiths GO, Baker J, Spector TD. Determinants of pressure pain threshold in adult twins: evidence that shared environmental influences predominate. Pain 1997;73(2):253-7.

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  • 1996

    Masud T, Mootoosamy I, McCloskey EV, O’Sullivan MP, Whitby EP, King D, Matson MB, Doyle DV, Spector TD. Assessment of osteopenia from spine radiographs using two different methods: the Chingford Study. Br J Radiol 1996;69(821):451-6.

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  • 1995

    Masud T, Jawed S, Doyle DV, Spector TD. A population study of the screening potential of assessment of trabecular pattern of the femoral neck (Singh index): the Chingford Study. Br J Radiol 1995;68(808):389-93.

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  • 1994

    Hall GM, Daniels M, Huskisson EC, Spector TD. A randomised controlled trial of the effect of hormone replacement therapy on disease activity in postmenopausal rheumatoid arthritis. Ann Rheum Dis 1994;53(2):112-6

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  • 1993

    da Silva JA, Colville-Nash EV, Doyle DV, Kanis JA. Inflammation-induced cartilage degradation in female rodents. Protective role of sex hormones. Arthritis Rheum. 1993;36(7):1007-13.

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  • 1992

    Spector TD, Brennan P, Harris PA, Studd JW, Silman AJ. Do current regimes of hormone replacement therapy protect against subsequent fractures? Osteoporos Int 1992;2(5):219-24. 

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  • 1991

    Chander CL, Spector TD. Oestrogens, joint disease, and cartilage. Ann Rheum Dis 1991;50(3):139-40 [PubMed]. Hart DJ, Spector TD, Brown P, Wilson P, Doyle DV, Silman AJ. Clinical signs of early osteoarthritis: reproducibility and relation to x ray changes in 541 women in the general population. Ann Rheum Dis 1991;50(7):467-70 [PubMed]. Scott DL, Spector TD. The […]

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  • 1990

    Hazes JM, Silman AJ, Brand R, Spector TD, Walker DJ, Vandenbroucke JP. Influence of oral contraception on the occurrence of rheumatoid arthritis in female sibs. Scand J Rheumatol 1990;19(4):306-10 [PubMed]. Hochberg MC, Spector TD. Epidemiology of rheumatoid arthritis: update. Epidemiol Rev 1990;12:247-52 [PubMed]. Spector TD. Rheumatoid arthritis. Rheum Dis Clin North Am 1990;16(3):513-37 [PubMed]. Spector […]

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  • 1989

    Hazes JM, Silman AJ, Brand R, Spector TD, Walker DJ, Vandenbroucke JP. A case-control study of oral contraceptive use in women with rheumatoid arthritis and their unaffected sisters. Br J Rheumatol 1989;28 Suppl 1:35- [PubMed]. Scott DL, Spector TD, Pullar T, McConkey B. What should we hope to achieve when treating rheumatoid arthritis? [see comments]. […]

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  • 1988

    Spector TD, Thompson PW, Evans SJ, Scott PL. Are slow-acting antirheumatic drugs being given earlier in rheumatoid arthritis? [letter]. Br J Rheumatol 1988;27(6):498-9 [PubMed]. Spector TD, Scott DL. What happens to patients with rheumatoid arthritis? The long-term outcome of treatment. Clin Rheumatol 1988;7(3):315-30 [PubMed]. Spector TD, Brown GC, Silman AJ. Increased rates of previous hysterectomy […]

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  • 1987

    Spector TD, Silman AJ. Oral contraceptives and rheumatoid arthritis. Bias in observational studies of cause-effect relationships [letter]. J Chronic Dis 1987;40(11):1063-7 [PubMed]. Spector TD, Silman AJ. Does the negative association between rheumatoid arthritis and schizophrenia provide clues to the aetiology of rheumatoid arthritis? Br J Rheumatol 1987;26(4):307-10 [PubMed]. Spector TD, Perry LA, Tubb G, Huskisson […]

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